Author

A. L. Mammen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

H. B. Larman· 3 shared T. E. Lloyd· 3 shared D. R. Monaco· 2 shared I. Pinal-Fernandez· 2 shared M. Roederer· 2 shared S. Jayaraman· 2 shared A. A. R. Tobian· 1 shared A. Chen· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

H. B. Larman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptomic profiling reveals distinct subsets of immune checkpoint inhibitor-induced myositis

I. Pinal-Fernandez, A. Quintana, J. Milisenda, M. Casal-Dominguez, S. Munoz-Braceras, A. Derfoul, J. Torres-Ruiz, K. Pak, S. Del Orso, F. Naz, G. Gutierrez-Cruz, M. Milone, S. Shelly, Y. Duque-Jaimez, E. Tobias-Baraja, , A. L. Mammen

This study identifies three distinct transcriptomic subsets of immune checkpoint inhibitor-induced myositis using bulk and single-nuclei RNA sequencing.

bioRxiv · Dec 12, 2022Immunology

Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors

J. W. Angkeow, D. R. Monaco, A. Chen, T. Venkataraman, S. Jayaraman, C. Valencia, B. M. Sie, T. Liechti, P. N. Farhadi, G. Funez-dePagnier, C. A. Sherman-Baust, M. Q. Wong, C. L. Sears, P. J. Simner, J. L. Round, , H. B. Larman

The paper uses PhIP-Seq with a ToxScan library to profile antibody responses to toxins and virulence factors in 1,000 individuals, finding MHC-II locus associations and novel anti-flagellin links to juvenile dermatomyositis.

bioRxiv · Oct 1, 2021 · PreprintImmunology

Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis

K. A. Britson, J. P. Ling, K. E. Braunstein, J. M. Montagne, J. M. Kastenschmidt, A. Wilson, C. Ikenaga, W. Tsao, I. Pinal-Fernandez, K. A. Russel, N. Reed, K. R. Wagner, L. W. Ostrow, A. M. Corse, A. L. Mammen, , T. E. Lloyd

Depletion of T cells in a xenograft model of sporadic inclusion body myositis suppresses inflammation but not TDP-43 pathology or muscle degeneration.

bioRxiv · Apr 9, 2021Pathology

Neutralizing IFNL3 Autoantibodies in Severe COVID-19 Identified Using Molecular Indexing of Proteins by Self-Assembly

J. J. Credle, J. Gunn, P. Sangkhapreecha, D. R. Monaco, X. A. Zheng, H.-J. Tsai, A. Wilbon, W. R. Morgenlander, Y. Dong, S. Jayaraman, L. Tosi, B. Parekkadan, A. N. Baer, M. Roederer, E. M. Bloch, , H. B. Larman

MIPSA identifies neutralizing IFNL3 autoantibodies in severe COVID-19 patients by profiling autoantibodies against DNA-barcoded proteins.

bioRxiv · Mar 2, 2021 · PreprintImmunology