Author

C. L. Sears

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. J. Simmons· 2 shared J. T. Roland· 2 shared M. J. Shrubsole· 2 shared N. O. Markham· 2 shared R. J. Coffey· 2 shared A. Chen· 1 shared A. L. Mammen· 1 shared A. N. Southard-Smith· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. J. Simmons

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors

J. W. Angkeow, D. R. Monaco, A. Chen, T. Venkataraman, S. Jayaraman, C. Valencia, B. M. Sie, T. Liechti, P. N. Farhadi, G. Funez-dePagnier, C. A. Sherman-Baust, M. Q. Wong, C. L. Sears, P. J. Simner, J. L. Round, , H. B. Larman

The paper uses PhIP-Seq with a ToxScan library to profile antibody responses to toxins and virulence factors in 1,000 individuals, finding MHC-II locus associations and novel anti-flagellin links to juvenile dermatomyositis.

bioRxiv · Oct 1, 2021 · PreprintImmunology

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

B. Chen, E. T. McKinley, A. J. Simmons, M. A. Ramirez, X. Zhu, A. N. Southard-Smith, N. O. Markham, Q. Sheng, J. Drewes, Y. Xu, C. N. Heiser, Y. Zhou, F. Revetta, L. D. Berry, W. Zheng, , K. Lau

The paper creates a single-cell atlas of colorectal pre-cancerous polyps, identifying distinct molecular programs in adenomas and sessile serrated lesions and their associations with CRC subtypes.

bioRxiv · Jan 11, 2021Cancer Biology

Clinically adaptable polymer enables simultaneous spatial analysis of colonic tissues and biofilms

M. C. Macedonia, J. L. Drewes, N. O. Markham, A. J. Simmons, J. T. Roland, P. N. Vega, C. R. Scurrah, R. J. Coffey, M. J. Shrubsole, C. L. Sears, K. S. Lau

This paper introduces a clinically adaptable polymer that preserves spatial compartments of colonic tissues and biofilms for simultaneous analysis.

bioRxiv · Apr 15, 2020Cell Biology