Author

I. Pinal-Fernandez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

A. L. Mammen· 2 shared A. Mammen· 2 shared A. Rajan· 2 shared C. Zhao· 2 shared H. B. Larman· 2 shared J. Milisenda· 2 shared L. Christopher-Stine· 2 shared T. E. Lloyd· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. L. Mammen

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Author profile →

4 papers

Recent·Most cited

Transcriptomic profiling reveals distinct subsets of immune checkpoint inhibitor-induced myositis

I. Pinal-Fernandez, A. Quintana, J. Milisenda, M. Casal-Dominguez, S. Munoz-Braceras, A. Derfoul, J. Torres-Ruiz, K. Pak, S. Del Orso, F. Naz, G. Gutierrez-Cruz, M. Milone, S. Shelly, Y. Duque-Jaimez, E. Tobias-Baraja, , A. L. Mammen

This study identifies three distinct transcriptomic subsets of immune checkpoint inhibitor-induced myositis using bulk and single-nuclei RNA sequencing.

bioRxiv · Dec 12, 2022Immunology

Contrasting autoimmune and treatment effects reveals baseline set points of immune toxicity following checkpoint inhibitor treatment

C. Zhao, M. P. Mule, A. J. Martins, I. Pinal-Fernandez, R. N. Donahue, J. Chen, J. Schlom, J. L. Gulley, A. Mammen, J. S. Tsang, A. Rajan

The paper identifies pre-treatment immune signatures associated with immune-related adverse events (irAEs) in thymic cancer patients receiving checkpoint inhibitors using CITE-seq.

bioRxiv · Jun 5, 2022 · PreprintImmunology

Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis

K. A. Britson, J. P. Ling, K. E. Braunstein, J. M. Montagne, J. M. Kastenschmidt, A. Wilson, C. Ikenaga, W. Tsao, I. Pinal-Fernandez, K. A. Russel, N. Reed, K. R. Wagner, L. W. Ostrow, A. M. Corse, A. L. Mammen, , T. E. Lloyd

Depletion of T cells in a xenograft model of sporadic inclusion body myositis suppresses inflammation but not TDP-43 pathology or muscle degeneration.

bioRxiv · Apr 9, 2021Pathology

Ultra-Efficient Short Read Sequencing of T Cell Receptor Repertoires

J. Montagne, X. Zheng, I. Pinal-Fernandez, J. Milisenda, L. Christopher-Stine, T. Lloyd, A. Mammen, H. B. Larman

This paper introduces FR3AK-seq, a cost-effective method for TCR CDR3 repertoire analysis, showing it is sensitive and comparable to industry standards.

bioRxiv · Feb 5, 2020 · PreprintImmunology