Author

A. L. Pyke

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Emily TrimmiD· 1 shared Kristy Red‐HorseiD· 1 shared Kyle M. LohiD· 1 shared Lay Teng AngiD· 1 shared Meenakshi ChakrabortyiD· 1 shared Xiaochen FaniD· 1 shared Zhainib A Amir-UgokweiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Emily TrimmORCID

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1 paper

Recent·Most cited

Human vein-to-artery endothelial cell fate transition is driven by VEGF/ERK activation and PI3K inhibition

Zhainib A Amir-Ugokwe, A. L. Pyke, Emily Trimm, Meenakshi Chakraborty, Xiaochen Fan, Lay Teng Ang, Kyle M. Loh, Kristy Red‐Horse

A stem cell-derived human vein-to-artery endothelial conversion model mirrors angiogenesis-derived embryonic arteries; VEGF plus PI3K inhibition alone yields 92% DLL4+CXCR4+ endothelium by 48 hours.

Development · Jun 15, 2026Peer-reviewedDevelopmental Biology✦ In-depth digest