Author

A. L. R. Premlal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

G. Seumois· 2 shared G.-Y. Seo· 2 shared J. Greenbaum· 2 shared M. Kronenberg· 2 shared M. P. Murray· 2 shared P. Vijayanand· 2 shared A. Chawla· 1 shared A. Sethi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

G. Seumois

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression

J. S. Dolina, J. Lee, S. E. Brightman, S. McArdle, S. M. Hall, R. R. Thota, M. Lanka, A. L. R. Premlal, J. A. Greenbaum, E. E. W. Cohen, B. Peters, S. P. Schoenberger

This study shows that combining CD4+/CD8+ T cell neoantigen vaccination with immune checkpoint blockade overcomes resistance and enables tumor regression in low TMB cancers.

bioRxiv · May 6, 2023 · PreprintImmunology

Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity

S. Chandra, G. Ascui, T. Riffelmacher, A. Chawla, C. Ramirez-Suastegui, V. C. Castelan, G. Seumois, H. Simon, M. P. Murray, G.-Y. Seo, A. L. R. Premlal, G. Verstichel, Y. Li, C.-H. Lin, J. Greenbaum, , M. Kronenberg

This study identifies MAIT cell heterogeneity in mice and humans through single-cell RNA sequencing and metabolic analysis, revealing distinct transcriptomes and metabolic states in different tissues and species.

bioRxiv · Dec 20, 2021 · PreprintImmunology

Transcriptome and Chromatin Landscape of iNKT cells are Shaped by Subset Differentiation and Antigen Exposure

M. P. Murray, I. Engel, G. Seumois, S. H. de la Mata, S. L. Rosales, A. Sethi, A. L. R. Premlal, G.-Y. Seo, J. Greenbaum, P. Vijayanand, J. P. Scott-Browne, M. Kronenberg

This study examines how iNKT cell subsets change in gene programs and chromatin structure across tissues and after antigen exposure, revealing long-term adaptability.

bioRxiv · Oct 27, 2020Immunology