Author

A. L. Wyllie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

D. M. Weinberger· 2 shared A. Casanovas-Massana· 1 shared A. Iwasaki· 1 shared A. J. Wijmega-Monsuur· 1 shared A. Ko· 1 shared A. Moore· 1 shared A. Tothpal· 1 shared A. van der Ende· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. M. Weinberger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Magnetic Bead-Based Separation (MBS) of Pneumococcal Serotypes

A. York, E. T. Huynh, S. Mbodj, D. Yolda-Carr, M. Hislop, H. Echlin, J. W. Rosch, D. M. Weinberger, A. L. Wyllie

This paper develops a magnetic bead-based method to enrich pneumococcal serotypes from mixed samples, achieving enrichment from 0.1% to 10-90% in dual serotype mixtures.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology

Pneumococcal genetic variability influences age-dependent bacterial carriage

P. H. C. Kremer, B. Ferwerda, H. J. Bootsma, N. Y. Rots, A. J. Wijmega-Monsuur, L. A. M. Sanders, K. Trzcinski, A. L. Wyllie, P. Turner, A. van der Ende, M. C. Brouwer, S. D. Bentley, D. van de Beek, J. A. Lees

This study identifies pneumococcal genetic factors associated with age-dependent carriage, suggesting vaccine formulations should target serotypes rather than proteins.

bioRxiv · Mar 3, 2021 · PreprintMicrobiology

Detection of SARS-CoV-2 RNA by multiplex RT-qPCR

E. Kudo, B. Israelow, C. Vogels, P. Lu, A. L. Wyllie, M. Tokuyama, A. Venkataraman, D. E. Brackney, I. Ott, M. Petrone, R. Earnest, S. Lapidus, C. Muenker, A. Moore, A. Casanovas-Massana, , A. Iwasaki

This paper develops a multiplex RT-qPCR assay for SARS-CoV-2 detection that uses existing primer/probe sets and reduces reagents, costs, time, and labor compared to singleplex assays.

bioRxiv · Jun 16, 2020Microbiology

Growth characteristics of pneumococcus vary with the chemical composition of the capsule and with environmental conditions

A. Tothpal, K. Desobry, S. Joshi, A. L. Wyllie, D. M. Weinberger

The paper examines how pneumococcus growth varies with environmental conditions and capsule composition, finding associations between growth characteristics and serotype prevalence.

bioRxiv · Feb 27, 2019 · PreprintMicrobiology