Author

M. C. Brouwer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. van de Beek· 2 shared A. J. Wijmega-Monsuur· 1 shared A. Kadiloglu· 1 shared A. L. Wyllie· 1 shared A. Proust· 1 shared A. van der Ende· 1 shared B. Ferwerda· 1 shared B. W. Wren· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. van de Beek

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The Streptococcus pneumoniae transcriptome in patient cerebrospinal fluid identifies novel virulence factors required for meningitis

E. C. Wall, J.-A. Guerra-Assuncao, M. Yang, R. Konig, T. Audshasai, A. Proust, R. Aprianto, E. Ramos-Sevillano, G. Ercoli, N. Bordin, V. S. Agostinho-Terra, J.-W. Veening, D. G. Lalloo, B. W. Wren, R. J. Wilkinson, , J. S. Brown

The paper uses RNA sequencing of cerebrospinal fluid from meningitis patients to identify S. pneumoniae virulence factors, finding two genes linked to increased mortality and reduced infection persistence.

bioRxiv · Apr 30, 2024 · PreprintMicrobiology

Pneumococcal genetic variability influences age-dependent bacterial carriage

P. H. C. Kremer, B. Ferwerda, H. J. Bootsma, N. Y. Rots, A. J. Wijmega-Monsuur, L. A. M. Sanders, K. Trzcinski, A. L. Wyllie, P. Turner, A. van der Ende, M. C. Brouwer, S. D. Bentley, D. van de Beek, J. A. Lees

This study identifies pneumococcal genetic factors associated with age-dependent carriage, suggesting vaccine formulations should target serotypes rather than proteins.

bioRxiv · Mar 3, 2021 · PreprintMicrobiology