A novel resistance pathway for calcineurin inhibitors in the human pathogenic Mucorales Mucor circinelloides
S. Vellanki, R. B. Billmyre, A. Lorenzen, M. Campbell, B. Turner, E. Y. Huh, J. Heitman, S. C. Lee
This paper identifies a novel resistance mechanism in Mucor circinelloides involving the bycA gene, which promotes yeast growth and resistance to calcineurin inhibitors through a cAMP-independent pathway.
mBio · Feb 25, 2020Peer-reviewedMicrobiology