Duplication and overexpression of the genes encoding a beta 1,3-glucan synthase confer the intrinsic resistance to echinocandin in Mucor circinelloides
S. C. Lee, A. Garcia, E. Y. Huh
This study identifies gene duplication and calcineurin-mediated overexpression of fks genes as mechanisms of intrinsic echinocandin resistance in Mucor circinelloides.
bioRxiv · Jan 3, 2022 · PreprintMicrobiology