Author

A. M. Brokaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. D. Tischler· 1 shared A. Kaushansky· 1 shared A. M. Block· 1 shared E. K. K. Glennon· 1 shared F. D. Mast· 1 shared H. S. Kain· 1 shared I. Cestari· 1 shared J. D. Aitchison· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. D. Tischler

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Mycobacterium tuberculosis requires the outer membrane lipid phthiocerol dimycocerosate for starvation-induced antibiotic tolerance

A. M. Block, S. B. Namugenyi, N. P. Palani, A. M. Brokaw, L. Zhang, K. B. Beckman, A. D. Tischler

This paper identifies phthiocerol dimycocerosate (PDIM) as essential for Mycobacterium tuberculosis antibiotic tolerance under nutrient starvation, suggesting PDIM synthesis as a target to enhance antibiotic efficacy.

bioRxiv · Jul 7, 2022Microbiology

Plasmodium secretion induces hepatocyte lysosome exocytosis and promotes parasite entry

K. Vijayan, I. Cestari, F. D. Mast, E. K. K. Glennon, S. M. McDermott, H. S. Kain, A. M. Brokaw, J. D. Aitchison, K. Stuart, A. Kaushansky

This study shows that Plasmodium sporozoites induce hepatocyte lysosome exocytosis through secreted factors, facilitating parasite entry and highlighting parallels with Trypanosoma cruzi infection.

bioRxiv · Apr 25, 2019Cell Biology