Author

F. D. Mast

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 4 Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. D. Aitchison· 6 shared A. Kaushansky· 3 shared J. P. Olivier· 3 shared M. P. Rout· 3 shared A. Sali· 2 shared B. T. Chait· 2 shared H. S. Kain· 2 shared K. Vijayan· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersCell Biology

J. D. Aitchison

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus

N. E. Ketaren, F. D. Mast, P. C. Fridy, J. P. Olivier, T. Sanyal, A. Sali, B. T. Chait, M. P. Rout, J. Aitchison

The paper shows that nanobodies against ancestral SARS-CoV-2 spike protein remain effective against recent variants, including omicron sublineages and emerging XBB/BQ.1.1 variants.

bioRxiv · Jul 14, 2023Biochemistry

The nucleoporin Nup170 mediates subtelomeric gene silencing through the Ctf18-RFC complex and PCNA

S. Kumar, M. L. Neal, S. Li, A. T. Navare, F. D. Mast, M. P. Rout, J. D. Aitchison

This study identifies Nup170's role in subtelomeric gene silencing by regulating PCNA levels through the Ctf18-RFC complex and Mlp1/Mlp2-dependent NPC subpopulations.

bioRxiv · Jun 17, 2022 · PreprintCell Biology

Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2

F. D. Mast, P. C. Fridy, N. E. Ketaren, J. Wang, E. Y. Jacobs, J. P. Olivier, T. Sanyal, K. R. Molloy, F. Schmidt, M. Rutkowska, Y. Weisblum, L. M. Rich, E. R. Vanderwall, N. Dambrauskas, V. Vigdorovich, , M. P. Rout

This paper presents a large repertoire of high-affinity nanobodies against SARS-CoV-2 Spike protein with potent neutralization properties and resistance to viral variants.

bioRxiv · Apr 8, 2021Biochemistry

Dengue activates mTORC2 signaling to counteract apoptosis and maximize viral replication

C. C. Carter, J. P. Olivier, A. Kaushansky, F. D. Mast, J. D. Aitchison

This study shows that dengue virus activates mTORC2 to prevent apoptosis and enhance viral replication.

bioRxiv · Sep 22, 2020Microbiology

A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.

K. Vijayan, N. Arang, L. Wei, R. Morrison, R. Geiger, R. K. Parks, A. J. Lewis, F. D. Mast, A. N. Douglass, H. S. Kain, J. D. Aitchison, J. S. Johnson, A. Aderem, A. Kaushansky

bioRxiv · Aug 31, 2020Cell Biology

Plasmodium secretion induces hepatocyte lysosome exocytosis and promotes parasite entry

K. Vijayan, I. Cestari, F. D. Mast, E. K. K. Glennon, S. M. McDermott, H. S. Kain, A. M. Brokaw, J. D. Aitchison, K. Stuart, A. Kaushansky

This study shows that Plasmodium sporozoites induce hepatocyte lysosome exocytosis through secreted factors, facilitating parasite entry and highlighting parallels with Trypanosoma cruzi infection.

bioRxiv · Apr 25, 2019Cell Biology

ESCRT-III acts in scissioning new peroxisomes from the ER

F. D. Mast, T. Herricks, K. M. Strehler, L. R. Miller, R. A. Saleem, R. A. Rachubinski, J. D. Aitchison

This study identifies ESCRT-III proteins as essential for scissioning preperoxisomal vesicles from the ER during peroxisome biogenesis.

bioRxiv · Jan 19, 2018Cell Biology