Author

S. M. McDermott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

J. D. Aitchison· 3 shared J. Carnes· 2 shared K. D. Stuart· 2 shared K. V. Schwedhelm· 2 shared M. J. McElrath· 2 shared M. L. Neal· 2 shared N. Hertoghs· 2 shared S. C. De Rosa· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

J. D. Aitchison

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Author profile →

3 papers

Recent·Most cited

Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge

D. A. Oyong, F. J. Duffy, M. L. Neal, Y. Du, J. Carnes, K. V. Schwedhelm, N. Hertoghs, S.-H. Jun, H. Miller, J. D. Aitchison, S. C. De Rosa, E. W. Newell, M. J. McElrath, S. M. McDermott, K. D. Stuart

The paper identifies distinct immune responses associated with vaccination status and protection outcomes after malaria challenge using transcriptome and cellular profiling.

bioRxiv · Dec 9, 2022 · PreprintImmunology

Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity

Y. Du, N. Hertoghs, J. Carnes, S. M. McDermott, M. L. Neal, K. V. Schwedhelm, M. J. McElrath, S. C. De Rosa, J. D. Aitchison, K. D. Stuart

The paper analyzes immune responses to malaria vaccination and finds that excessive early inflammation correlates with impaired immunity.

bioRxiv · Jul 28, 2021Immunology

Plasmodium secretion induces hepatocyte lysosome exocytosis and promotes parasite entry

K. Vijayan, I. Cestari, F. D. Mast, E. K. K. Glennon, S. M. McDermott, H. S. Kain, A. M. Brokaw, J. D. Aitchison, K. Stuart, A. Kaushansky

This study shows that Plasmodium sporozoites induce hepatocyte lysosome exocytosis through secreted factors, facilitating parasite entry and highlighting parallels with Trypanosoma cruzi infection.

bioRxiv · Apr 25, 2019Cell Biology