Modulation of triple artemisinin-based combination therapy pharmacodynamics by Plasmodium falciparum genotype
M. R. Ansbro, Z. Itkin, L. Chen, G. Zahoranszky-Kohalmi, C. Amaratunga, O. Miotto, T. Peryea, C. V. Hobbs, S. Suon, J. M. S, A. M. Dondorp, R. W. van der Pluijm, T. Wellems, A. Simeonov, R. T. Eastman
The paper evaluates drug-drug interactions in triple artemisinin-based combination therapies (TACTs) using an in vitro high-throughput process to identify genotype-dependent susceptibility and antagonism.
ACS Pharmacology & Translational Science · Dec 11, 2020Peer-reviewedMicrobiology