Author

M. J. Delves

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:plant (other)· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

J. Baum· 2 shared S. Yahiya· 2 shared U. Straschil· 2 shared A. Barnard· 1 shared A. E. Barry· 1 shared A. F. Cowman· 1 shared A. Khomiak· 1 shared A. M. Dondorp· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. Baum

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1

M. G. Dans, C. Boulet, G. M. Watson, W. Nguyen, J. M. Dziekan, C. Evelyn, K. Reaksudsan, S. Mehra, Z. Razook, N. D. Geoghegan, M. J. Mlodzianoski, C. D. Goodman, D. B. Ling, T. K. Jonsdottir, J. Tong, , P. R. Gilson

The paper identifies aryl amino acetamides that inhibit Plasmodium falciparum ring development by targeting PfSTART1, a lipid transfer protein, and shows these inhibitors block parasite transmission.

bioRxiv · Nov 2, 2023 · PreprintCell Biology

Machine Learning-based Phenotypic Imaging to Characterise the Targetable Biology of Plasmodium falciparum Male Gametocytes for the Development of Transmission-Blocking Antimalarials

O. Tsebriy, A. Khomiak, C. Miguel-Blanco, P. C. Sparkes, M. Gioli, M. Santelli, E. Whitley, F.-J. Gamo, M. J. Delves

The paper uses machine learning to analyze fluorescence microscopy images of Plasmodium falciparum gametocytes, characterizing the cellular effects of transmission-blocking molecules.

bioRxiv · Apr 22, 2023 · PreprintMicrobiology

Plasmodium falciparum protein Pfs16 is a target for transmission-blocking antimalarial drug development

S. Yahiya, C. N. Saunders, U. Straschil, O. J. Fischer, A. Rueda-Zubiaurre, S. Haase, G. Vizcay-Barrena, S. Jordan, S. Hassan, M. J. Delves, E. W. Tate, A. Barnard, M. J. Fuchter, J. Baum

This study identifies Pfs16 as the cellular target of the N-4HCS compound DDD01035881, which blocks Plasmodium male gamete formation.

bioRxiv · Jun 14, 2021Microbiology

Artemisinin-resistant malaria parasites show enhanced transmission to mosquitoes under drug pressure

K. Witmer, F. A. Dahalan, M. J. Delves, S. Yahiya, O. J. Watson, U. Straschil, D. Chiwcharoen, B. Sornboon, S. Pukrittayakamee, R. D. Pearson, V. Howick, M. Lawniczak, N. J. White, A. M. Dondorp, L. C. Okell, , J. Baum

Artemisinin-resistant malaria parasites show reduced sensitivity to transmission-blocking effects of artemisinin drugs, increasing their transmission to mosquitoes under drug pressure.

bioRxiv · Feb 4, 2020Microbiology