Author

A. M. English

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. L. Hughes· 4 shared J. M. Shaw· 3 shared A. Hughes· 1 shared B. Kornmann· 1 shared G. Odorizzi· 1 shared J. A. Maschek· 1 shared J. E. Cox· 1 shared L. Vandermeer· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersCell Biology

A. L. Hughes

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Author profile →

5 papers

Recent·Most cited

Mitochondrial-Derived Compartments are Multilamellar Domains that Encase Membrane Cargo and Cytosol

Z. N. Wilson, M. West, A. M. English, G. Odorizzi, A. Hughes

The paper uses electron tomography and time-lapse fluorescence microscopy to show that mitochondrial-derived compartments (MDCs) form from outer mitochondrial membrane extensions that sequester membrane cargo and cytosol.

bioRxiv · Jul 7, 2023Cell Biology

Genetic Screen Uncovers a Dual Role for Phospholipids in Mitochondrial-Derived Compartment Biogenesis

T. Xiao, A. M. English, J. A. Maschek, J. E. Cox, A. L. Hughes

The paper identifies distinct roles for cardiolipin and phosphatidylethanolamine in mitochondrial-derived compartment (MDC) biogenesis, showing cardiolipin is required for MDC formation while phosphatidylethanolamine depletion triggers it during amino acid stress.

bioRxiv · Feb 16, 2023 · PreprintCell Biology

Amino Acids Promote Mitochondrial-Derived Compartment Formation in Mammalian Cells

M. H. Schuler, A. M. English, L. Vandermeer, J. M. Shaw, A. L. Hughes

This study identifies mammalian Mitochondrial-Derived Compartments (MDCs) that form in response to amino acid excess and are conserved from yeast.

bioRxiv · Dec 23, 2020 · PreprintCell Biology

ER-Mitochondria Contacts Promote Mitochondrial-Derived Compartment Biogenesis

A. M. English, B. Kornmann, J. M. Shaw, A. L. Hughes

The paper identifies ER-mitochondria contacts as sites for mitochondrial-derived compartment (MDC) biogenesis, showing it requires ERMES and Gem1 GTPase.

Journal of Cell Biology · Oct 22, 2020Peer-reviewedCell Biology

Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid Stress

M.-H. Schuler, A. M. English, T. J. Campbell, J. M. Shaw, A. L. Hughes

The paper identifies mitochondrial-derived compartments (MDCs) as structures that protect cells from amino acid stress by sequestering Tom70 and coordinating with the MVB pathway.

bioRxiv · Mar 13, 2020Cell Biology