Author

A. M. Griffin

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Biochemistry· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. M. Johnson· 1 shared C. Barrington· 1 shared E. W. Hartwick· 1 shared J. S. Kieft· 1 shared J. T. Roberts· 1 shared M. M. Balas· 1 shared R. Bettcher· 1 shared S. K. Wu· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. M. Johnson

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1 paper

Recent·Most cited

RNA matchmaking remodels lncRNA structure and promotes PRC2 activity

M. M. Balas, E. W. Hartwick, C. Barrington, J. T. Roberts, S. K. Wu, R. Bettcher, A. M. Griffin, J. S. Kieft, A. M. Johnson

The paper shows that RNA matchmaking between HOTAIR and target gene RNAs relieves PRC2 inhibition, promoting its activity through structural changes and hnRNP B1-mediated interactions.

bioRxiv · Apr 13, 2020 · PreprintBiochemistry