Author

E. W. Hartwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. S. Kieft· 2 shared R. L. Gonzalez· 2 shared A. M. Griffin· 1 shared A. M. Johnson· 1 shared A. MacFadden· 1 shared B. D. Hobson· 1 shared C. Barrington· 1 shared C. D. Kinz-Thompson· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

J. S. Kieft

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Author profile →

4 papers

Recent·Most cited

The mechanism of mRNA activation

R. C. Gentry, N. A. Ide, V. M. Comunale, E. W. Hartwick, C. D. Kinz-Thompson, R. L. Gonzalez

This study uses single-molecule fluorescence imaging to investigate how eIF4F recognizes and activates mRNA caps, revealing allosteric communication and subunit functions in the process.

bioRxiv · Nov 15, 2023 · PreprintBiophysics

Structural Diversity and Phylogenetic Distribution of Valyl tRNA-like Structures in Viruses

M. E. Sherlock, E. W. Hartwick, A. MacFadden, J. S. Kieft

The paper investigates the structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses, identifying structural heterogeneity and cases of anticodon switching.

bioRxiv · Jun 19, 2020Biochemistry

Elongation Inhibitors do not Prevent the Release of Puromycylated Nascent Polypeptide Chains from Ribosomes

B. D. Hobson, L. Kong, E. W. Hartwick, R. L. Gonzalez, P. A. Sims

This study shows that elongation inhibitors do not prevent the release of puromycylated nascent polypeptides from ribosomes, challenging the use of anti-puromycin staining to determine translation sites.

bioRxiv · Jun 15, 2020Biochemistry

RNA matchmaking remodels lncRNA structure and promotes PRC2 activity

M. M. Balas, E. W. Hartwick, C. Barrington, J. T. Roberts, S. K. Wu, R. Bettcher, A. M. Griffin, J. S. Kieft, A. M. Johnson

The paper shows that RNA matchmaking between HOTAIR and target gene RNAs relieves PRC2 inhibition, promoting its activity through structural changes and hnRNP B1-mediated interactions.

bioRxiv · Apr 13, 2020 · PreprintBiochemistry