Author

A. M. Olmo-Fontanez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

J. B. Torrelles· 5 shared A. Garcia-Vilanova· 3 shared J. Turner· 3 shared A. Akhter· 2 shared C. A. Headley· 2 shared D. J. Maselli· 2 shared J. M. Scordo· 2 shared J. Peters· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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5 shared papersImmunology

J. B. Torrelles

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5 papers

Recent·Most cited

Mitochondrial Transplantation promotes protective effector and memory CD4+ T cell response during Mycobacterium tuberculosis infection and diminishes exhaustion and senescence in elderly CD4+ T cells

C. A. Headley, s. Guatam, A. M. Olmo-Fontanez, A. Garcia-Vilanova, V. Dwivedi, A. A. Schami, S. Weintraub, P. S. Tsao, J. B. Torrelles, J. Turner

This study shows mitochondrial transplantation enhances CD4+ T cell function in elderly individuals and mice infected with Mycobacterium tuberculosis by reducing exhaustion and senescence.

bioRxiv · Jan 24, 2024 · PreprintImmunology

HIV Infection impairs the Host Response to Mycobacterium tuberculosis Infection by altering Surfactant Protein D function in the Human Lung Alveolar Mucosa

A. Akhter, J. Moliva, A. K. Azad, A. M. Olmo-Fontanez, A. Garcia-Vilanova, J. M. Scordo, M. Gavrilin, P. Diaz, J. Endsley, S. Weintraub, L. Schlesinger, M. Wewers, J. B. Torrelles

bioRxiv · Oct 1, 2023 · PreprintCell Biology

Exposure of Mycobacterium tuberculosis to human alveolar lining fluid shows temporal and strain-specific adaptation to the lung environment

A. A. Guardia, A. G. Vilanova, A. M. Schami, A. M. Olmo-Fontanez, A. Hicks, J. Peters, D. J. Maselli, M. D. Wewers, Y. Wang, J. B. Torrelles

This study exposes M.tb strains to human alveolar lining fluid and finds strain-specific and time-dependent gene expression changes, particularly in lipid metabolism and cholesterol degradation.

bioRxiv · Sep 27, 2023 · PreprintMicrobiology

Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis growth in alveolar epithelial cells and bacterial translocation into the cytosol

A. M. Olmo-Fontanez, J. M. Scordo, A. Garcia-Vilanova, D. J. Maselli, J. Peters, B. I. Restrepo, D. L. Clemens, J. Turner, L. S. Schlesinger, J. B. Torrelles

bioRxiv · May 12, 2021 · PreprintImmunology

Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging.

C. A. Headley, S. Gautam, A. M. Olmo-Fontanez, A. M. Garcia-Vilanova, V. Dwivedi, A. Akhter, A. Schami, K. Chiem, R. Ault, H. Zhang, H. Cai, A. A. Whigham, J. A. Delgado, A. A. Hicks, P. Tsao, , J. Turner

This study transfers functional mitochondria into aged CD4+ T cells, improving their metabolism, reducing oxidative stress, and enhancing immune function against infections.

bioRxiv · Feb 21, 2021Immunology