Post-translational modification by the Pgf glycosylation machinery modulates Streptococcus mutans physiology and virulence
N. de Mojana di Cologna, S. Andresen, S. Samaddar, S. A. Archer-Hartmann, T. Ganguly, J. K. Kajfasz, B. A. Garcia, I. Saengpet, A. M. Peterson, P. Azadi, C. M. Szymanski, J. A. Lemos, J. A. Abranches
This study shows that the Pgf glycosylation machinery in Streptococcus mutans modifies surface proteins, affecting biofilm formation and virulence, with phosphorylation compensating for glycosylation loss.
bioRxiv · Oct 10, 2022 · PreprintMicrobiology