Author

J. K. Kajfasz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Organism:mouse· 1

Frequent Co-Authors

J. A. Lemos· 6 shared J. Abranches· 5 shared T. Ganguly· 5 shared A. M. Peterson· 2 shared A. Flores-Mireles· 1 shared A. Peterson· 1 shared B. A. Garcia· 1 shared C. Katrak· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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6 shared papersMicrobiology

J. A. Lemos

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Author profile →

6 papers

Recent·Most cited

Post-translational modification by the Pgf glycosylation machinery modulates Streptococcus mutans physiology and virulence

N. de Mojana di Cologna, S. Andresen, S. Samaddar, S. A. Archer-Hartmann, T. Ganguly, J. K. Kajfasz, B. A. Garcia, I. Saengpet, A. M. Peterson, P. Azadi, C. M. Szymanski, J. A. Lemos, J. A. Abranches

This study shows that the Pgf glycosylation machinery in Streptococcus mutans modifies surface proteins, affecting biofilm formation and virulence, with phosphorylation compensating for glycosylation loss.

bioRxiv · Oct 10, 2022 · PreprintMicrobiology

ZccE is a Novel P-type ATPase That Protects Streptococcus mutans Against Zinc Intoxication

T. Ganguly, A. Peterson, M. Burkholder, J. K. Kajfasz, J. Abranches, J. A. Lemos

This study identifies ZccE, a P-type ATPase in Streptococcus mutans, as a key factor in its high zinc tolerance and resistance to multiple metal ions, offering a potential target for antimicrobial therapies.

bioRxiv · Mar 29, 2022Microbiology

c-di-AMP is essential for the virulence of Enterococcus faecalis

S. Kundra, L. N. Lam, J. K. Kajfasz, L. Casella, M. J. Andersen, J. Abranches, A. Flores-Mireles, J. A. Lemos

This study shows that c-di-AMP is essential for the virulence of Enterococcus faecalis, as its absence or accumulation impairs cell fitness and pathogenicity in multiple models.

bioRxiv · May 19, 2021Microbiology

Zinc Import Mediated by AdcABC is Critical for Colonization of the Dental Biofilm by Streptococcus mutans in an Animal Model

T. Ganguly, A. M. Peterson, J. K. Kajfasz, J. Abranches, J. A. Lemos

This study identifies AdcABC as the sole high-affinity zinc importer in S. mutans and shows its critical role in biofilm colonization and survival under zinc-depleted conditions.

bioRxiv · Jan 22, 2021Microbiology

Increased oxidative stress tolerance of a spontaneously-occurring perR gene mutation in Streptococcus mutans UA159

J. K. Kajfasz, P. Zuber, T. Ganguly, J. Abranches, J. A. Lemos

The paper identifies a perR gene mutation in S. mutans UA159 that increases oxidative stress tolerance, but shows minimal transcriptional impact, highlighting the need for strain authentication.

bioRxiv · Sep 24, 2020Microbiology

Manganese uptake, mediated by SloABC and MntH, is essential for the fitness of Streptococcus mutans

J. A. Lemos, J. K. Kajfasz, T. Ganguly, G. A. Spatafora, J. Abranches, C. Katrak, J. A. Vargas, L. T. Wright, Z. T. Peters

This study shows that manganese uptake via SloABC and MntH is critical for Streptococcus mutans growth and virulence under manganese restriction.

bioRxiv · Oct 24, 2019Microbiology