Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin
G. Khelashvili, A. N. Pillai, J. Lee, K. Pandey, A. M. Payne, Z. Siegel, M. A. Cuendet, T. R. Lewis, V. Y. Arshavsky, J. Broichhagen, J. Levitz, A. K. Menon
The paper investigates the dimerization behavior of F220C rhodopsin mutant and wild-type opsin in vitro and in the plasma membrane, finding that the mutant forms a unique dimer with distinct conformational features.
bioRxiv · Dec 28, 2020Biophysics