ImmunologybioRxiv
SARS-CoV-2 immune complex triggers human monocyte necroptosis
L. Santos, K. H. Antunes, G. Cassao…·B. Porto
This study shows SARS-CoV-2 and its immune complexes induce monocyte necroptosis via RIPK3 and MLKL, with Syk kinase involvement, and links elevated LDH to COVID-19 pathogenesis.
DOI 10.1016/j.intimp.2023.109954