Author

A. P. Geballe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:chicken / avian· 1 Research Focus:clustering· 1

Frequent Co-Authors

S. J. Child· 2 shared A. Bayer· 1 shared A. L. Greninger· 1 shared A. M. Ladha· 1 shared A. T. Olson· 1 shared C. B. Lim· 1 shared C. Smith· 1 shared G. Brennan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

S. J. Child

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB

A. Bayer, S. J. Child, H. S. Malik, A. P. Geballe

The paper identifies a single amino acid variant in MxB that determines HSV-1 restriction in humans, showing that this variant is absent in other primates and has recently become common in humans.

bioRxiv · May 30, 2023Microbiology

Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation

A. T. Olson, Y. Kang, A. M. Ladha, C. B. Lim, M. Lagunoff, T. S. Gujral, A. P. Geballe

This study identifies kinases regulating KSHV reactivation using a polypharmacology-based screen, revealing both pro-lytic and latency-promoting kinases.

bioRxiv · Feb 1, 2023 · PreprintMicrobiology

Gene amplification acts as a molecular foothold to facilitate cross-species adaptation and evasion of multiple antiviral pathways

S. Banerjee, C. Smith, A. P. Geballe, S. Rothenburg, J. O. Kitzman, G. Brennan

This study shows gene amplification helps a virus adapt to new species by overcoming antiviral defenses.

bioRxiv · Jun 6, 2022Evolutionary Biology

Rapid adaptation to human protein kinase R by a unique genomic rearrangement in rhesus cytomegalovirus.

S. J. Child, A. L. Greninger, A. P. Geballe

This paper shows that RhCMV adapts to human PKR by acquiring a genomic duplication that enhances rTRS1 expression and PKR pathway inhibition, improving replication in human cells.

bioRxiv · Nov 6, 2020Microbiology