Conserved anti-inflammatory effects and sensing of butyrate in zebrafish
P. M. Cholan, A. Han, B. R. Woodie, A. R. Kurz, W. J. Britton, L. Ye, Z. C. Holmes, J. R. McCann, L. A. David, J. F. Rawls, S. H. Oehlers
The paper shows that butyrate, a short-chain fatty acid, has anti-inflammatory effects in zebrafish by reducing neutrophil and M1 macrophage recruitment to wounds, and identifies a conserved receptor for butyrate sensing in fish.
bioRxiv · May 13, 2020Immunology