Interactions between fungal hyaluronic acid and host CD44 promote internalization by recruiting host autophagy proteins to forming phagosomes
S. Ding, A. Pandey, X. Feng, J. Yang, L. F. da Costa, R. B. Mouneimne, A. Rice-Ficht, S. L. Bell, R. O. Watson, K. L. Patrick, Q.-M. Qin, T. A. Ficht, P. de Figueiredo
This paper shows fungal hyaluronic acid interacts with host CD44 to recruit autophagy proteins to phagosomes, promoting fungal internalization via a Ca2+ -CaMKKβ-AMPK-ULK1 signaling pathway.
iScience · Mar 1, 2021Peer-reviewedMicrobiology