The Set1 complex is dimeric and acts with Jhd2 demethylation to convey symmetrical H3K4 trimethylation
R. Choudhury, S. Singh, S. Arumugam, A. Roguev, A. F. Stewart
This paper shows that the yeast Set1 complex is dimeric, leading to symmetric H3K4me3, and that Jhd2 demethylase removes asymmetric H3K4me3, working together to establish epigenetic symmetry.
bioRxiv · Nov 24, 2018Cell Biology