N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers
G. A. Lueg, M. Faronato, A. Gorelik, A. Goya Grocin, E. Caamano-Gutierrez, F. Falciani, R. Solari, R. Carr, A. S. Bell, E. Bartlett, J. A. Hutton, M. Llorian-Sopena, P. Chakravarty, B. Brzezicha, M. Janz, , E. W. Tate
N-myristoyltransferase inhibition causes mitochondrial dysfunction and cell death in MYC-deregulated cancers through post-transcriptional failure in complex I synthesis.
bioRxiv · Mar 20, 2021 · PreprintCancer Biology