Author

A. S. De Groot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Moise· 2 shared W. D. Martin· 2 shared A. E. Sluder· 1 shared A. Garritsen· 1 shared A. R. Henry· 1 shared A. S. Fahad· 1 shared A. Scholzen· 1 shared B. J. DeKosky· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersEvolutionary Biology

L. Moise

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Author profile →

3 papers

Recent·Most cited

Diversity and Evolution of Computationally Predicted T Cell Epitopes against Human Respiratory Syncytial Virus

J. Chen, S. Tan, V. Avadhanula, L. Moise, P. A. Piedra, A. S. De Groot, J. Bahl

This study computationally predicts T cell epitopes in RSV proteins and finds divergent epitope patterns between RSV-A and RSV-B strains, suggesting vaccine updates may be needed for RSV-B.

bioRxiv · Jun 29, 2022Evolutionary Biology

Human antibody immune responses are personalized by selective removal of MHC-II peptide epitopes

M. Gutierrez-Gonzalez, A. S. Fahad, M. Ardito, P. Nanaware, L. Lu, E. Normandin, B. Madan, J. Tivin, E. Coates, A. R. Henry, F. Laboune, B. S. Graham, D. C. Douek, J. E. Ledgerwood, J. R. Mascola, , B. J. DeKosky

The paper shows that MHC-II epitope removal from BCRs correlates with antibody development, T cell help, and long-term serum antibody secretion.

bioRxiv · Jan 15, 2021 · PreprintImmunology

Coxiella burnetii epitope-specific T-cell responses in chronic Q fever patients

A. Scholzen, G. Richard, L. Moise, E. Hartman, C. P. Bleeker-Rovers, P. M. Reeves, S. Raju Paul, W. D. Martin, A. S. De Groot, M. C. Poznansky, A. E. Sluder, A. Garritsen

The paper examines T-cell responses to Coxiella burnetii epitopes in chronic Q fever patients, finding overlapping epitope recognition with convalescents and broader ex vivo responses in treated patients.

bioRxiv · Mar 20, 2019Immunology