A. S. Zhovmer

This study shows that septins regulate T cell migration modes by switching between amoeboid and mesenchymal movement, with mesenchymal migration relying on microtubules and dynein motors.

This study identifies dynein-powered locomotion as a complementary mechanism to actomyosin-driven movement in metastatic breast cancer cells, showing its necessity and sufficiency in 3D migration.

This paper identifies septins as key regulators of amoeboid motility in T cells by enabling microenvironment sensing and actomyosin partitioning through steric interactions with collagen fibers.

The paper shows dynein and kinesin motors balance microtubule network mechanics, affecting cell shape, adhesion, and mechanosensing through opposing actions on microtubule organization.