Author

A. Sahm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

M. Bens· 3 shared A. Cellerino· 2 shared H. A. Kestler· 2 shared M. Goerlach· 2 shared M. Groth· 2 shared M. Platzer· 2 shared S. Hoffmann· 2 shared A. Lucas-Sanchez· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersEvolutionary Biology

M. Bens

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4 papers

Recent·Most cited

Non-aging despite high mutation rate - genomic insights into the evolution of Hydra

A. Sahm, K. Riege, M. Groth, M. Bens, J. M. Kraus, M. Fischer, H. A. Kestler, C. Englert, R. Schaible, M. Platzer, S. Hoffmann

This study examines Hydra's genome to understand its non-aging phenotype, finding no reduced mutation rate and identifying genes under selection related to regeneration and metabolism.

bioRxiv · May 18, 2022 · PreprintEvolutionary Biology

The analysis of epigenomic evolution

A. Sahm, P. Koch, S. Horvath, S. Hoffmann

The paper applies phylogenetic methods to epigenetic data, showing DNA methylation conservation and its correlation with transcription factor binding density in great apes.

bioRxiv · Mar 3, 2021Evolutionary Biology

Clownfishes are a genetic model of exceptional longevity and reveal molecular convergence in the evolution of lifespan

A. Sahm, P. Almaida-Pagan, M. Bens, M. Mutalipassi, A. Lucas-Sanchez, J. de Costa Ruiz, M. Goerlach, A. Cellerino

The paper identifies genetic correlates of exceptional longevity in clownfishes and reveals molecular convergence with other long-lived species.

bioRxiv · Aug 3, 2018Evolutionary Biology

Long-lived rodents reveal signatures of positive selection in genes associated with lifespan and eusociality

A. Sahm, M. Bens, K. Szafranski, S. Holtze, M. Groth, M. Goerlach, C. Calkhoven, C. Mueller, M. Schwab, H. A. Kestler, A. Cellerino, H. Burda, T. Hildebrandt, P. Dammann, M. Platzer

The paper identifies genes under positive selection in long-lived rodents, linking them to mTOR-related processes, immune function, and antioxidant defense, and finds expression patterns consistent with antagonistic pleiotropy in aging.

bioRxiv · Oct 8, 2017Evolutionary Biology