Ubiquitin-driven protein condensation initiates clathrin-mediated endocytosis
F. Yuan, S. Gollapudi, K. Day, G. Ashby, A. Sangani, B. Malady, L. Wang, E. M. Lafer, J. Huibregtse, J. Stachowiak
This paper shows that ubiquitin stabilizes Eps15 condensates, which are essential for clathrin-mediated endocytosis, and that ubiquitylation regulates the dynamics of endocytic assemblies.
bioRxiv · Aug 21, 2023 · PreprintCell Biology