Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
C. Walker, A. Chandrasekaran, D. Mansour, K. Graham, A. Torres, L. Wang, E. M. Lafer, P. Rangamani, J. Stachowiak
The paper shows that actin-binding proteins forming liquid-like condensates can polymerize and bundle actin filaments, expanding the known set of proteins capable of this function.
bioRxiv · May 4, 2024 · PreprintBiophysics
K. Graham, A. Chandrasekaran, L. Wang, N. Yang, E. M. Lafer, P. Rangamani, J. C. Stachowiak
This study shows that liquid-like condensates containing both actin branching and bundling proteins can modulate the competition between these processes, leading to organized actin structures similar to those in migrating cells.
Proceedings of the National Academy of Sciences · Jan 11, 2024Peer-reviewedBiophysics
F. Yuan, S. Gollapudi, K. Day, G. Ashby, A. Sangani, B. Malady, L. Wang, E. M. Lafer, J. Huibregtse, J. Stachowiak
This paper shows that ubiquitin stabilizes Eps15 condensates, which are essential for clathrin-mediated endocytosis, and that ubiquitylation regulates the dynamics of endocytic assemblies.
bioRxiv · Aug 21, 2023 · PreprintCell Biology
A. Kamatar, J. P. K. Bravo, F. Yuan, L. Wang, E. M. Lafer, D. W. Taylor, J. Stachowiak, S. H. Parekh
This study shows that intrinsically disordered proteins can undergo phase separation on lipid droplet surfaces, forming liquid-like protein-rich phases.
bioRxiv · Jun 28, 2023Biophysics
J. R. Houser, H. W. Cho, C. C. Hayden, N. Yang, L. Wang, E. M. Lafer, D. Thirumalai, J. C. Stachowiak
This study measures steric pressure generated by intrinsically disordered domains of AP180 at membrane surfaces, finding that they produce significant pressure through entropic and electrostatic mechanisms, independent of molecular weight.
Biophysical Journal · Sep 1, 2022Peer-reviewedBiophysics
K. D. Graham, A. Chandrasekaran, L. Wang, A. Ladak, E. M. Lafer, P. Rangamani, J. C. Stachowiak
This study shows VASP forms liquid-like droplets that drive actin polymerization and bundling by creating actin-rich rings that transition into linear bundles.
bioRxiv · May 9, 2022Biophysics
K. J. Day, G. Kago, L. Wang, J. B. Richter, C. C. Hayden, E. M. Lafer, J. C. Stachowiak
The paper shows that weak, liquid-like interactions between Eps15 and Fcho1 enable efficient endocytosis by promoting dynamic protein assembly and preventing stalling of vesicle budding.
bioRxiv · Dec 2, 2019Cell Biology
W. T. Snead, W. F. Zeno, G. Kago, R. W. Perkins, J. B. Richter, C. Zhao, E. M. Lafer, J. C. Stachowiak
The paper shows that BAR domain-containing proteins drive membrane fission by crowding disordered domains, challenging the idea that BAR scaffolds stabilize membranes.
bioRxiv · Jul 16, 2018Biophysics