A. Selyutina

TRIM5α restriction of HIV-1-N74D viruses in lymphocytes is caused by a loss of cyclophilin A protection

This study shows that HIV-1-N74D viruses lose infectivity in CD4+ T cells due to reduced protection from cyclophilin A against TRIM5hu restriction.

Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating

This study shows HIV-1 cores enter the nucleus before reverse transcription and uncoating, suggesting these processes occur in nuclear compartments.

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5alpha Binding to the viral Core