Author

A. Stoddard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Ramamoorthy· 4 shared B. Sahoo· 4 shared C. A. Fierke· 2 shared K. Yasuhara· 2 shared M. Bekier· 2 shared M. Ivanova· 2 shared T. Genjo· 2 shared Y. Wang· 2 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersBiophysics

A. Ramamoorthy

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Author profile →

4 papers

Recent·Most cited

High Throughput Screening at the Membrane Interface Reveals New Inhibitors of Amyloid-β

S. Cox, B. Lam, A. Prasad, H. Marietta, N. Stander, J. Joel, B. Sahoo, F. Guo, A. Stoddard, M. Ivanova, A. Ramamoorthy

This study identifies 5 small molecules that inhibit amyloid-β aggregation at the cell-membrane interface, which is relevant for Alzheimer's disease.

bioRxiv · Nov 24, 2019Biochemistry

Apolipoprotein A-I Mimetic 4F Peptide Generates Amyloid Cytotoxins by Forming Hetero-oligomers with β-amyloid

B. Sahoo, M. Bekier, Z. Liu, V. Kocman, A. Stoddard, G. Anantharamaiah, J. Nowick, C. Fierke, Y. Wang, A. Ramamoorthy

The paper investigates how the 4F peptide interacts with β-amyloid to form toxic heteromers, reducing aggregation kinetics and increasing neurotoxicity.

bioRxiv · Aug 4, 2019 · PreprintBiophysics

Alzheimer’s Amyloid-Beta Intermediates Generated by Polymer-Nanodiscs

B. Sahoo, T. Genjo, M. Bekier, S. J. Cox, A. Stoddard, M. Ivanova, K. Yasuhara, C. A. Fierke, Y. Wang, A. Ramamoorthy

This study uses PMA-nanodiscs to study Aβ1-40 aggregation, showing they trap intermediates and reduce neurotoxicity of oligomers.

bioRxiv · Oct 5, 2018Biophysics

Cationic polymethacrylate-copolymer acts as an agonist for beta-amyloid and antagonist for amylin fibrillation

B. Sahoo, T. Genjo, A. Stoddard, K. Yasuhara, C. A. Fierke, A. Ramamoorthy

This study shows a cationic polymer promotes Aβ40 fibrillation and inhibits hIAPP aggregation through electrostatic interactions and structural restraint.

bioRxiv · Aug 27, 2018Biophysics