Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses
G. Brar, N. A. Farhat, A. Sukhina, A. K. Lam, Y. H. Kim, T. Hsu, L. Tong, W. W. Lin, C. F. Ware, M. A. Blackman, R. Sun, T.-T. Wu
This paper develops a herpesvirus vaccine by deleting immune evasion genes to enhance immunogenicity and safety, showing durable protection against latency in a mouse model.
bioRxiv · Apr 13, 2020Microbiology