Author

A. T. Waickman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 8

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. R. Currier· 5 shared S. J. Thomas· 4 shared H. Friberg· 3 shared T. P. Endy· 3 shared A. Wegman· 2 shared H. Fang· 2 shared J. Q. Lu· 2 shared K. L. Newell· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

J. R. Currier

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

DENV-specific IgA contributes protective and non-pathologic function during antibody-dependent enhancement of DENV infection

A. Wegman, M. Waldran, L. E. Bahr, J. Q. Lu, K. E. Baxter, S. J. Thomas, A. T. Waickman

This study shows that DENV-specific IgA neutralizes the virus and prevents antibody-dependent enhancement, unlike IgG, and highlights its protective role in dengue infection.

PLOS Pathogens · Aug 28, 2023Peer-reviewedImmunology

Soluble NS1 antagonizes IgG- and IgA-mediated monocytic phagocytosis of DENV infected cells

M. J. Waldran, A. D. Wegman, L. E. Bahr, J. R. Currier, A. T. Waickman

This study shows soluble NS1 inhibits IgG- and IgA-mediated phagocytosis of DENV-infected cells by blocking opsonization.

bioRxiv · Dec 17, 2022Immunology

Evolution of inflammation and immunity in a dengue virus 1 human infection model

A. T. Waickman, J. Q. Lu, H. Fang, M. Waldran, C. Gebo, J. R. Currier, L. Van Wesenbeeck, N. Verpoorten, O. Lenz, L. Tambuyzer, G. Herrera-Taracena, M. Van Loock, T. P. Endy, S. J. Thomas

This study analyzes the immune and virologic responses in humans infected with DENV-1, revealing new insights into the kinetics and composition of immune responses and gene modules involved in DENV infection.

bioRxiv · Feb 10, 2022Immunology

mRNA-1273 vaccination protects against SARS-CoV-2 elicited lung inflammation in non-human primates

A. T. Waickman, K. Victor, K. L. Newell, T. L. Li, H. Friberg, K. Foulds, M. Roederer, D. L. Bolton, J. R. Currier, R. Seder

mRNA-1273 vaccination reduces lower respiratory tract inflammation in SARS-CoV-2 challenged rhesus macaques by limiting viral replication and inflammatory gene expression.

bioRxiv · Dec 24, 2021Immunology

Simultaneous analysis of antigen-specific B and T cells after SARS-CoV-2 infection and vaccination

K. L. Newell, M. J. Waldran, S. J. Thomas, T. P. Endy, A. T. Waickman

The paper introduces a method to simultaneously detect SARS-CoV-2 antigen-specific B and T cells using flow cytometry, showing its application in studying vaccination effects on immune responses.

bioRxiv · Dec 8, 2021Immunology

Monomeric IgA antagonizes IgG-mediated enhancement of DENV infection

A. Wegman, H. Fang, A. L. Rothman, S. J. Thomas, T. P. Endy, M. K. McCracken, J. R. Currier, H. Friberg, G. D. Gromowski, A. T. Waickman

This study shows that monomeric IgA can neutralize DENV and block IgG-mediated antibody-dependent enhancement (ADE) in vitro.

bioRxiv · Sep 14, 2021Immunology

Wnt/β-catenin regulates alloreactive T cells for the treatment of hematological malignancies

M. Mammadli, R. Harris, S. Mahmudlu, A. Verma, A. May, R. Dhawan, A. T. Waickman, J. M. Sen, M. Karimi

This study shows that β-catenin regulates donor T cells in allo-HSCT, reducing GVHD while preserving GVL effects through altered cytokine production and cytotoxicity.

bioRxiv · Apr 12, 2021 · PreprintImmunology

Dissecting the heterogeneity of DENV vaccine-elicited cellular immunity using single-cell RNA sequencing and cellular metabolic profiling

A. T. Waickman, K. Victor, T. Li, K. Hatch, W. Rutvisuttinnunt, C. Medin, B. Gabriel, R. G. Jarman, H. Friberg, J. R. Currier

This study uses single-cell RNA sequencing and metabolic profiling to identify metabolic signatures of durable T cell memory in DENV vaccine responses.

bioRxiv · Jan 3, 2019Immunology