Author

A. V. Pisliakov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

V. H. Cowling· 2 shared C. A. Carvalheda· 1 shared J. A. Bueren-Calabuig· 1 shared M. Bage· 1 shared M. G. Bage· 1 shared o. N. Vickery· 1 shared R. Almohammed· 1 shared S. A. Zaidi· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

V. H. Cowling

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3 papers

Recent·Most cited

Identification of novel RNA Polymerase II CTD interaction sites on the mRNA Capping Enzyme

M. G. Bage, R. Almohammed, V. H. Cowling, A. V. Pisliakov

The paper identifies novel RNA Polymerase II CTD interaction sites on the mRNA Capping Enzyme using computational methods and validates them experimentally, showing conservation across eukaryotic taxa.

bioRxiv · Feb 25, 2020 · PreprintBiophysics

Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations

J. A. Bueren-Calabuig, M. Bage, V. H. Cowling, A. V. Pisliakov

This study uses molecular dynamics simulations to reveal how RAM allosterically activates RNMT by stabilizing optimal substrate binding conformations and facilitating cooperative cap and AdoMet binding.

bioRxiv · Mar 3, 2019Biophysics

Intracellular Passage Of Na+ In An Active State G Protein Coupled Receptor

o. N. Vickery, C. A. Carvalheda, S. A. Zaidi, A. V. Pisliakov, V. Katritch, U. Zachariae

This study shows that Na+ ion movement from an extracellular binding site to the cytosol is a key step in GPCR activation, stabilizing active-state conformations.

bioRxiv · Jul 21, 2017Biophysics