Author

O. N. Vickery

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:human· 4 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:multiome· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

U. Zachariae· 3 shared A. V. Pisliakov· 1 shared C. A. Carvalheda· 1 shared C. M. Ives· 1 shared G. Tamburrino· 1 shared M. S. Sansom· 1 shared N. J. Thomson· 1 shared P. J. Stansfeld· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersBiophysics

U. Zachariae

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Author profile →

5 papers

Recent·Most cited

CG2AT2: An Enhanced Fragment-based approach for Serial Multi-scale Molecular Dynamics simulations

O. N. Vickery, P. J. Stansfeld

The paper introduces CG2AT2, a fragment-based method to convert coarse-grained macromolecular complexes to atomistic resolution, validated on eleven diverse systems.

bioRxiv · Mar 25, 2021Biochemistry

Ion-water coupling controls class A GPCR signal transduction pathways

N. J. Thomson, O. N. Vickery, C. M. Ives, U. Zachariae

The paper uses molecular dynamics simulations to show that ion-water coupling is essential for GPCR signal transduction, with sodium acting as a master switch.

bioRxiv · Aug 28, 2020 · PreprintBiophysics

Insights into Membrane Protein-Lipid Interactions from Free Energy Calculations

R. A. Corey, O. N. Vickery, M. S. Sansom, P. Stansfeld

This study uses three computational methods to calculate the free energies of protein-lipid interactions in bacterial and mammalian systems, showing good agreement between the techniques.

bioRxiv · Jun 14, 2019Biochemistry

Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE

G. Tamburrino, S. Llabres, O. N. Vickery, S. J. Pitt, U. Zachariae

This study characterizes the electrophysiological properties of MtrE and MtrC in Neisseria gonorrhoeae, showing their role in antibiotic efflux and identifying potential targets for inhibitors.

bioRxiv · Oct 25, 2017Biophysics

Intracellular Passage Of Na+ In An Active State G Protein Coupled Receptor

o. N. Vickery, C. A. Carvalheda, S. A. Zaidi, A. V. Pisliakov, V. Katritch, U. Zachariae

This study shows that Na+ ion movement from an extracellular binding site to the cytosol is a key step in GPCR activation, stabilizing active-state conformations.

bioRxiv · Jul 21, 2017Biophysics