Author

A. Vecchione

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

H. W. Li· 2 shared M. Sykes· 2 shared A. Ruiz· 1 shared B. E. Low· 1 shared D. Serreze· 1 shared E. Waffarn· 1 shared E. Y. Chavez· 1 shared G. A. Nauman· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

H. W. Li

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2 papers

Recent·Most cited

Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice

M. Khosravi-Maharlooei, A. Vecchione, N. Danzl, H. W. Li, G. Nauman, R. Madley, E. Waffarn, R. Winchester, A. Ruiz, X. Ding, G. Fousteri, M. Sykes

The paper shows that PD-1+CD4+ Tfh-like and Tph-like cells in human immune system mice drive autoimmune disease, with disease progression linked to HLA-restricted T cell-APC interactions.

bioRxiv · May 2, 2024Immunology

Interleukin-15 Receptor α Chain Knockout NOD-SCID mice have reduced numbers of NK cells, develop thymic lymphomas and fail to engraft human hematopoietic cells

A. Vecchione, G. A. Nauman, M. Khosravi Marharlooei, N. M. Danzl, H. W. Li, E. Y. Chavez, B. E. Low, M. V. Wiles, D. Serreze, L. Ding, M. Sykes

This study shows that NOD-SCID mice lacking IL15R have reduced NK cells, accelerated lymphoma, and poor human hematopoietic engraftment.

bioRxiv · Apr 22, 2021 · PreprintImmunology