Author

R. Winchester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Mor· 1 shared A. Ruiz· 1 shared A. Vecchione· 1 shared B. Henick· 1 shared C. E. Seidman· 1 shared E. Waffarn· 1 shared G. Fousteri· 1 shared G. Nauman· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Mor

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Author profile →

3 papers

Recent·Most cited

Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice

M. Khosravi-Maharlooei, A. Vecchione, N. Danzl, H. W. Li, G. Nauman, R. Madley, E. Waffarn, R. Winchester, A. Ruiz, X. Ding, G. Fousteri, M. Sykes

The paper shows that PD-1+CD4+ Tfh-like and Tph-like cells in human immune system mice drive autoimmune disease, with disease progression linked to HLA-restricted T cell-APC interactions.

bioRxiv · May 2, 2024Immunology

An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury

S. Fleischer, T. R. Nash, M. A. Tamargo, R. I. Lock, G. Venturini, M. Morsink, V. Li, M. J. Lamberti, P. L. Graney, M. Liberman, Y. Kim, R. Z. Zhuang, J. Whitehead, R. A. Friedman, R. SONI, , G. Vunjak-Novakovic

This study uses engineered human cardiac tissues to show how SLE autoantibodies affect myocardial injury through distinct binding patterns and functional effects on cardiac cells.

bioRxiv · Mar 7, 2024Bioengineering

PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis

J. Staube, S. Bukhari, S. Lerrer, R. Winchester, B. Henick, M. Dragovich, A. Mor

The paper identifies a novel subset of T cells in inflammatory arthritis associated with PD-1 signaling and finds genes linked to PD-1 downstream functions.

bioRxiv · Nov 16, 2023Immunology