Author

A. Verge de los Aires

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein structure prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

B. P. Fairfax· 1 shared C. A. Taylor· 1 shared E. Mahe· 1 shared H. Ruffieux· 1 shared I. Nassiri· 1 shared M. R. Middleton· 1 shared O. Tong· 1 shared P. K. Sharma· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

B. P. Fairfax

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintNov 15, 2020

Sensitivity to Immune Checkpoint Blockade and Progression-Free Survival is associated with baseline CD8+ T cell clone size and cytotoxicity

R. A. Watson, O. Tong, R. A. Cooper…·B. P. Fairfax

The paper uses single-cell and bulk RNA sequencing to show that CD8+ T cell subset and clone size influence gene expression responses to immune checkpoint blockade, and that pre-treatment cytotoxicity and clonality predict progression-free survival.

DOI 10.1101/2020.11.15.383786

humanscRNA-seq

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