Author

A. Vitali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:ecology & biodiversity· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. C. Rios· 1 shared A. Eggert· 1 shared A. G. Henssen· 1 shared A. Greppi· 1 shared A. Klaus· 1 shared A. Kuenkele· 1 shared B. Draper· 1 shared B. R. van 't Veld· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

A. C. Rios

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function

M. Barisa, E. Zappa, H. Muller, R. Shah, J. Buhl, B. Draper, C. Himsworth, C. Bowers, S. Munnings-Tomes, M. Nicolaidou, S. Morlando, K. Birley, C. Leboreiro-Babe, A. Vitali, L. Privitera, , J. Anderson

The paper evaluates how the functional avidity of anti-B7H3 CAR-T constructs relates to their ability to trigger effector function against tumors with varying antigen density.

bioRxiv · Feb 19, 2024Bioengineering

Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy

L. Grunewald, L. Andersch, K. Helmsauer, S. Schwiebert, A. Klaus, A. G. Henssen, T. Straka, M. Lodrini, S. G. Wicha, S. Fuchs, F. Hertwig, F. Westermann, A. Vitali, C. Caramel, G. Buechel, , A. Kuenkele

This paper shows that high MYCN levels in neuroblastoma reduce L1CAM expression, limiting CAR T cell efficacy, and that inhibiting MYCN with MLN8237 restores L1CAM and enhances CAR T cell activity.

bioRxiv · Jan 27, 2024Immunology

Invasive species modulate the structure and stability of a multilayer mutualistic network.

A. Vitali, S. Ruiz-Suarez, D. Vazquez, M. Schleuning, M. Rodriguez-Cabal, Y. Sasal, S. Pilosof

The paper examines how invasive ungulates alter the structure and stability of a pollination-seed dispersal multilayer network in Patagonia, showing reduced connectivity and increased vulnerability to disturbances.

bioRxiv · Dec 25, 2022Ecology