The paper introduces CISCM, a method to identify drug targets by immobilizing compounds on cellulose membranes and using proteomics, showing it can identify known targets quickly.

bioRxiv · Apr 3, 2022Biochemistry

A one-step biofunctionalization strategy of electrospun scaffolds enables spatially selective presentation of biological cues

P. Wieringa, A. Girao, R. Truckenmuller, A. Welle, S. Micera, R. van Wezel, L. Moroni

This paper introduces a one-step method to functionalize scaffolds with spatially selective biological cues, showing differential neurite growth in dorsal root ganglia.

bioRxiv · Nov 25, 2019Bioengineering

Sodium chloride is an ionic checkpoint for human Th2 cell responses and shapes the atopic skin microenvironment

J. Matthias, J. Maul, R. Noster, H. Meinl, Y.-Y. Chao, H. Gerstenberg, F. Jeschke, G. Gilles, A. Welle, J. Walter, K. Nordstroem, K. Eberhardt, D. Renisch, S. Donakonda, P. Knolle, , C. E. Zielinski

This study shows sodium chloride promotes Th2 cell responses and shapes the atopic skin microenvironment, suggesting it as a therapeutic target for Th2-mediated diseases.

bioRxiv · Aug 13, 2018Immunology