Cell BiologyProceedings of the National Academy of SciencesPeer-reviewed
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In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
Kevin M. Rose, Eric Herrmann, Eve V. Kakudji…·James H. Hurley
Cryo-ET of Parkin-expressing U2OS cells shows oligomycin/antimycin depolarization moves some ATP synthase to the inner boundary membrane, abolishes matrix calcium granules, and favors closed prohibitin domes.