Eric Herrmann

This study determines the structure of DFCP1 and shows it forms a barrier that concentrates PI3P for lysosomal repair.

The paper investigates how mitochondrial architecture changes during mtRNA surveillance failure, revealing stress body formation and spatial reorganization of mitochondrial components.

This study investigates the role of lysosomal components in tau seeding and finds that the PITT pathway and VPS13C are strongly involved in tau spread, while CASM and ALG-2 have more limited roles.

Cryo-ET of Parkin-expressing U2OS cells shows oligomycin/antimycin depolarization moves some ATP synthase to the inner boundary membrane, abolishes matrix calcium granules, and favors closed prohibitin domes.

The paper challenges a previously proposed structure of the prohibitin complex by showing that symmetry assumptions led to incorrect modeling of an asymmetric conformation.