Author

A. Yuan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Li· 2 shared Y. Wang· 2 shared B. Li· 1 shared B. Peng· 1 shared C. Wu· 1 shared F. Wang· 1 shared G. Shao· 1 shared H. Chen· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

J. Li

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and inhibits the Warburg effect in breast cancer

Z. Zhou, X. Zheng, J. Zhao, A. Yuan, G. Shao, B. Peng, M.-Q. Dong, Q. Xu, X. Xu, J. Li

This study identifies ULK1-mediated phosphorylation of PKM2 that inhibits O-GlcNAcylation and reduces the Warburg effect in breast cancer.

bioRxiv · Sep 14, 2023 · PreprintBiochemistry

DNA damage-induced YTHDC1 O-GlcNAcylation promotes homologous recombination by enhancing N6-methyladenosine binding

M. Li, J. Li, A. Yuan, W. Dong, S. Dong, Y.-G. Yang, Y. Wang, C. Wu, J. Li

This study shows that DNA damage-induced O-GlcNAcylation of YTHDC1 enhances its m6A binding, promoting homologous recombination and genome stability.

bioRxiv · Sep 3, 2022Biochemistry

Integrated single-cell sequencing analysis reveals peripheral immune landscape across the human lifespan

R. Tong, R. Li, Y. Zhao, L. Luo, J. Zhong, Z. Li, L. Wei, Y. Chen, J. Shi, Y. Gao, M. Sun, Y. Wang, Y. Lyu, A. Yuan, L. Sun, , J. Pu

This study uses single-cell sequencing to analyze immune cell dynamics across human lifespan, identifying age-related changes in T cell function, cell interactions, and B cell subsets.

bioRxiv · Jul 11, 2022 · PreprintImmunology