Lipin-1 contributes to IL-4 mediated macrophage polarization
S. Chandra, R. M. Schilke, C. M. R. Blackburn, A. Yurochko, R. Mirza, R. S. Scott, B. N. Finck, M. D. Woolard
This study shows that lipin-1's transcriptional co-regulator activity is necessary for macrophage polarization and wound healing, as its absence impairs IL-4 mediated gene expression and tissue repair.
bioRxiv · Dec 23, 2019Immunology