Author

A. Z. Cheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

R. S. Harris· 2 shared C. Attarian· 1 shared C. J. Bierle· 1 shared D. Sauter· 1 shared G. Galitska· 1 shared H. Nasser· 1 shared J. Yockteng-Melgar· 1 shared L. Frappier· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

R. S. Harris

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1

T. Ikeda, R. Shimizu, H. Nasser, M. A. Carpenter, A. Z. Cheng, W. L. Brown, D. Sauter, R. S. Harris

This study shows that HIV-1 Vif primarily degrades A3 enzymes to enable viral replication in THP-1 cells, as disrupting A3 proteins restores infectivity of Vif-deficient viruses.

bioRxiv · Mar 28, 2023 · PreprintMicrobiology

A Conserved Mechanism of APOBEC3 Relocalization by Herpesviral Ribonucleotide Reductase Large Subunits

A. Z. Cheng, S. Nobrega de Moraes, C. Attarian, J. Yockteng-Melgar, M. C. Jarvis, M. Biolatti, G. Galitska, V. Dell'Oste, L. Frappier, C. J. Bierle, S. A. Rice, R. S. Harris

This study shows that herpesviruses use viral ribonucleotide reductase subunits to relocalize APOBEC3B and APOBEC3A, suggesting a conserved mechanism to evade innate immunity.

bioRxiv · Sep 13, 2019Microbiology