Author

L. Frappier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Belter· 1 shared A. Z. Cheng· 1 shared B. Katschinski· 1 shared B. Sitek· 1 shared C. Attarian· 1 shared C. J. Bierle· 1 shared C. Schuler· 1 shared F. Maassen· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Belter

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2 papers

Recent·Most cited

The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T-cell recognition by targeting CIITA

F. Maassen, V. T. K. Le-Trilling, L. Betke, T. Bracht, C. Schuler, M. Bayer, A. Belter, T. Becker, B. Katschinski, L. Frappier, B. Sitek, K. Fleischhauer, M. Trilling

This study identifies pUS28 as a viral protein that inhibits CIITA-driven HLA-II expression, thereby blocking CD4+ T-cell recognition of HCMV-infected cells.

bioRxiv · Oct 17, 2023 · PreprintImmunology

A Conserved Mechanism of APOBEC3 Relocalization by Herpesviral Ribonucleotide Reductase Large Subunits

A. Z. Cheng, S. Nobrega de Moraes, C. Attarian, J. Yockteng-Melgar, M. C. Jarvis, M. Biolatti, G. Galitska, V. Dell'Oste, L. Frappier, C. J. Bierle, S. A. Rice, R. S. Harris

This study shows that herpesviruses use viral ribonucleotide reductase subunits to relocalize APOBEC3B and APOBEC3A, suggesting a conserved mechanism to evade innate immunity.

bioRxiv · Sep 13, 2019Microbiology