Author

A.-L. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Hu· 2 shared K. Wang· 2 shared N. Tang· 2 shared A. Zheng· 1 shared C.-J. Gu· 1 shared C.-L. He· 1 shared D. Chen· 1 shared F. Cao· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

J. Hu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia

Y.-W. Luo, J.-P. Zhou, H. Ji, A. Zheng, X. Wang, Z. Dai, Z. Luo, F. Cao, X.-Y. Wang, Y. Bai, D. Chen, Y. Chen, Q. Wang, Y. Yang, X. Zhang, , K.-F. Tang

This study shows that SARS-CoV-2 N protein reduces Dicer, XPO5, SRSF3, and hnRNPA3, leading to pneumonia, and that inhibitors can reverse this effect.

bioRxiv · Oct 3, 2023 · PreprintMicrobiology

Reduced infectivity but increased immune escape of the new SARS-CoV-2 variant of concern Omicron

J. Hu, P. Peng, K. Wu, Q.-x. Long, J. Chen, K. Wang, N. Tang, A.-l. Huang

This study assesses the infectivity and immune evasion of the Omicron SARS-CoV-2 variant using pseudotyped viruses and neutralizing assays against convalescent sera and vaccinated individuals.

bioRxiv · Dec 24, 2021 · PreprintMicrobiology

Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products in vitro

C.-L. He, L.-Y. Huang, K. Wang, C.-J. Gu, J. Hu, G.-J. Zhang, W. Xu, Y.-H. Xie, N. Tang, A.-L. Huang

This study identifies bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors through in vitro screening of natural products.

bioRxiv · Dec 13, 2020Microbiology